› 7ufv

X-ray diffraction
1.9Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195228 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DDB1- and CUL4-associated factor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 315 amino acids
Theoretical weight: 35.59 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9Y4B6 (Residues: 1077-1390; Coverage: 21%)
Gene names: DCAF1, KIAA0800, RIP, VPRBP

Ligands and Environments

2 bound ligands:
Ligand N6O 2 x N6O
Ligand UNX 1 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 49.14Å b: 87.875Å c: 73.807Å
α: 90° β: 98.54° γ: 90°
R-values:
R R work R free
0.207 0.204 0.254
Expression system: Spodoptera frugiperda

Quick links

Citations

4 citation in other articles

Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field.
Vulpetti et al. (2023)
3 more