Function and Biology Details
Reactions catalysed:
4-aminobutanal + NAD(+) + H(2)O = 4-aminobutanoate + NADH
Benzaldehyde + NAD(+) + H(2)O = benzoate + NADH
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH
Retinal + NAD(+) + H(2)O = retinoate + NADH
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
Aldehyde dehydrogenase 1A1 (preferred)
PDBe Complex ID:
PDB-CPX-132425 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldehyde dehydrogenase 1A1
Molecule details ›
Chain: A
Length: 501 amino acids
Theoretical weight: 54.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
Sequence domains: Aldehyde dehydrogenase family
Length: 501 amino acids
Theoretical weight: 54.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
- Canonical:
P00352 (Residues: 1-501; Coverage: 100%)
Sequence domains: Aldehyde dehydrogenase family
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
P422
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
