› 7upk

Electron Microscopy
2.8Å resolution

Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1A9

Released:
DOI: 10.2210/pdb7upk/pdb
PDB entry 7upk coloured by chain, front view.
PDB entry 7upk coloured by chain, side view.
PDB entry 7upk coloured by chain, top view.
Source organisms:
Primary publication:
Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Byrne PO, Fisher BE, Ambrozak DR, Blade EG, Tsybovsky Y, Graham BS, McLellan JS, Loomis RJ
OpenAccess logo Nat Commun 14 1494 (2023)
PMID: 36932063
Related structures: EMD-26668

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-212754 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Fusion glycoprotein F0 Chains: A, B, D
Molecule details ›
Chains: A, B, D
Length: 480 amino acids
Theoretical weight: 52.89 KDa
Source organism: Henipavirus nipahense
Expression system: Homo sapiens
Fab 1A9 heavy chain Chains: C, E, H
Molecule details ›
Chains: C, E, H
Length: 116 amino acids
Theoretical weight: 12.81 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Fab 1A9 light chain Chains: F, G, L
Molecule details ›
Chains: F, G, L
Length: 107 amino acids
Theoretical weight: 11.7 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.8Å
Relevant EMDB volumes: EMD-26668
Expression system: Homo sapiens

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Citations

1 review citation

Structural Studies of Henipavirus Glycoproteins.
May et al. (2024)
7 other articles