7ure

Electron Microscopy
3.19Å resolution

Human PORCN in complex with palmitoleoylated WNT3A peptide

Released:
Source organisms:
Related structures: EMD-26710

Function and Biology Details

Reaction catalysed:
(9Z)-hexadec-9-enoyl-CoA + [Wnt]-L-serine = CoA + [Wnt]-O-(9Z)-hexadec-9-enoyl-L-serine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-225690 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Protein-serine O-palmitoleoyltransferase porcupine Chain: A
Molecule details ›
Chain: A
Length: 464 amino acids
Theoretical weight: 52.82 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
2C11 light chain Chain: L
Molecule details ›
Chain: L
Length: 234 amino acids
Theoretical weight: 25.67 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
2C11 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 250 amino acids
Theoretical weight: 26.93 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Protein Wnt-3a Chain: B
Molecule details ›
Chain: B
Length: 22 amino acids
Theoretical weight: 2.53 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

3 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Resolution: 3.19Å
Relevant EMDB volumes: EMD-26710
Expression systems:
  • Homo sapiens
  • Not provided