› 7uth

Electron Microscopy
3.9Å resolution

Gea2 open/open conformation (composite structure)

Released:
DOI: 10.2210/pdb7uth/pdb
PDB entry 7uth coloured by chain, front view.
PDB entry 7uth coloured by chain, side view.
PDB entry 7uth coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural basis for activation of Arf1 at the Golgi complex.
Muccini AJ, Gustafson MA, Fromme JC
OpenAccess logo Cell Rep 40 111282 (2022)
PMID: 36044848
Related structures: EMD-26770

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153995 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ARF guanine-nucleotide exchange factor 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 1459 amino acids
Theoretical weight: 165.85 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P39993 (Residues: 1-1459; Coverage: 100%)
Gene names: GEA2, YEL022W
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-26770
Expression system: Komagataella pastoris

Quick links

Citations

6 citation in other articles

Sec7 regulatory domains scaffold autoinhibited and active conformations.
Brownfield et al. (2024)
5 more

2 mentions without citation

Structural basis for activation of Arf1 at the Golgi complex.
Muccini et al. (2022)
1 more