Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Interleukin-17, chordata
- Cystine-knot cytokine
- Interleukin-17 family
- Interleukin-17 receptor-like
- Interleukin-17 receptor A/B, FnIII-like domain 2 superfamily
- Interleukin-17 receptor, fibronectin-III-like domain 1
- Interleukin-17 receptor A/B, FnIII-like domain 1 superfamily
- Interleukin-17 receptor C/E, N-terminal
Structure analysis Details
Assembly composition:
hetero heptamer (preferred)
PDBe Complex ID:
PDB-CPX-172505 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Interleukin-17A
Molecule details ›
Chains: A, B, D, E
Length: 170 amino acids
Theoretical weight: 19.31 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Interleukin-17
Length: 170 amino acids
Theoretical weight: 19.31 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q16552 (Residues: 24-155; Coverage: 100%)
Sequence domains: Interleukin-17
Interleukin-17 receptor A
Molecule details ›
Chains: C, F
Length: 319 amino acids
Theoretical weight: 36.89 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt: Gene names: IL17R, IL17RA
Sequence domains:
Length: 319 amino acids
Theoretical weight: 36.89 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt: Gene names: IL17R, IL17RA
Sequence domains:
Interleukin-17 receptor C
Molecule details ›
Chain: G
Length: 479 amino acids
Theoretical weight: 53.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt: Gene names: IL17RC, UNQ6118/PRO20040/PRO38901
Sequence domains: Interleukin-17 receptor extracellular region
Length: 479 amino acids
Theoretical weight: 53.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt: Gene names: IL17RC, UNQ6118/PRO20040/PRO38901
Sequence domains: Interleukin-17 receptor extracellular region
