Protein Data Bank in Europe

Chain: A
Length: 2549 amino acids
Theoretical weight: 289.26 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

• Canonical: P42345 (Residues: 1-2549; Coverage: 100%)

Gene names: FRAP, FRAP1, FRAP2, MTOR, RAFT1, RAPT1
Sequence domains:

• Serine/threonine-protein kinase mTOR domain
• FAT domain
• FKBP12-rapamycin binding domain
• Phosphatidylinositol 3- and 4-kinase
• FATC domain

Chain: B
Length: 326 amino acids
Theoretical weight: 35.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

• Canonical: Q9BVC4 (Residues: 1-326; Coverage: 100%)

Gene names: GBL, LST8, MLST8
Sequence domains: WD domain, G-beta repeat

Chain: C
Length: 1335 amino acids
Theoretical weight: 149.2 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

• Canonical: Q8N122 (Residues: 1-1335; Coverage: 100%)

Gene names: KIAA1303, RAPTOR, RPTOR
Sequence domains:

• WD domain, G-beta repeat
• Raptor N-terminal CASPase like domain
• HEAT repeat

Chains: D, K
Length: 313 amino acids
Theoretical weight: 36.6 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

• Canonical: Q7L523 (Residues: 1-313; Coverage: 100%)

Gene name: RRAGA
Sequence domains: Gtr1/RagA G protein conserved region

Chains: E, L
Length: 399 amino acids
Theoretical weight: 44.3 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

• Canonical: Q9HB90 (Residues: 1-399; Coverage: 100%)

Gene name: RRAGC
Sequence domains: Gtr1/RagA G protein conserved region

Chains: F, M
Length: 161 amino acids
Theoretical weight: 17.76 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: Q6IAA8 (Residues: 1-161; Coverage: 100%)

Gene names: C11orf59, LAMTOR1, PDRO, PP7157
Sequence domains: Late endosomal/lysosomal adaptor and MAPK and MTOR activator

Chains: G, N
Length: 125 amino acids
Theoretical weight: 13.52 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: Q9Y2Q5 (Residues: 1-125; Coverage: 100%)

Gene names: HSPC003, LAMTOR2, MAPBPIP, ROBLD3
Sequence domains: Roadblock/LC7 domain

Chains: H, O
Length: 124 amino acids
Theoretical weight: 13.64 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: Q9UHA4 (Residues: 1-124; Coverage: 100%)

Gene names: LAMTOR3, MAP2K1IP1, MAPKSP1, PRO2783
Sequence domains: Mitogen-activated protein kinase kinase 1 interacting

Chains: I, P
Length: 99 amino acids
Theoretical weight: 10.75 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: Q0VGL1 (Residues: 1-99; Coverage: 100%)

Gene names: C7orf59, LAMTOR4

Chains: J, Q
Length: 91 amino acids
Theoretical weight: 9.62 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: O43504 (Residues: 1-91; Coverage: 100%)

Gene names: HBXIP, LAMTOR5, XIP
Sequence domains: Ragulator complex protein LAMTOR5

Chain: R
Length: 476 amino acids
Theoretical weight: 52.93 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

• Canonical: P19484 (Residues: 1-476; Coverage: 100%)

Gene names: BHLHE35, TFEB
Sequence domains:

• MITF/TFEB/TFEC/TFE3 N-terminus
• Helix-loop-helix DNA-binding domain
• Domain of unknown function (DUF3371)