Function and Biology Details
Reaction catalysed:
ATP + H(2)O + 4 H(+)(Side 1) = ADP + phosphate + 4 H(+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero 35-mer (preferred)
PDBe Complex ID:
PDB-CPX-235501 (preferred)
Entry contents:
17 distinct polypeptide molecules
Macromolecules (17 distinct):
H(+)-transporting two-sector ATPase
Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 617 amino acids
Theoretical weight: 68.34 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains:
Length: 617 amino acids
Theoretical weight: 68.34 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
D4A133 (Residues: 31-647; Coverage: 95%)
Sequence domains:
V-type proton ATPase subunit B, brain isoform
Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 511 amino acids
Theoretical weight: 56.61 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains:
Length: 511 amino acids
Theoretical weight: 56.61 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
P62815 (Residues: 1-511; Coverage: 100%)
Sequence domains:
V-type proton ATPase subunit C 1
Chain: G
Molecule details ›
Chain: G
Length: 382 amino acids
Theoretical weight: 43.96 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: V-ATPase subunit C
Length: 382 amino acids
Theoretical weight: 43.96 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
Q5FVI6 (Residues: 1-382; Coverage: 100%)
Sequence domains: V-ATPase subunit C
V-type proton ATPase subunit D
Chain: H
Molecule details ›
Chain: H
Length: 247 amino acids
Theoretical weight: 28.36 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: ATP synthase subunit D
Length: 247 amino acids
Theoretical weight: 28.36 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
Q6P503 (Residues: 1-247; Coverage: 100%)
Sequence domains: ATP synthase subunit D
V-type proton ATPase subunit E 1
Chains: I, J, K
Molecule details ›
Chains: I, J, K
Length: 226 amino acids
Theoretical weight: 26.17 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: ATP synthase (E/31 kDa) subunit
Length: 226 amino acids
Theoretical weight: 26.17 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
Q6PCU2 (Residues: 1-226; Coverage: 100%)
Sequence domains: ATP synthase (E/31 kDa) subunit
V-type proton ATPase subunit F
Chain: L
Molecule details ›
Chain: L
Length: 119 amino acids
Theoretical weight: 13.39 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: ATP synthase (F/14-kDa) subunit
Length: 119 amino acids
Theoretical weight: 13.39 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
P50408 (Residues: 1-119; Coverage: 100%)
Sequence domains: ATP synthase (F/14-kDa) subunit
V-type proton ATPase subunit G
Chains: M, N, O
Molecule details ›
Chains: M, N, O
Length: 118 amino acids
Theoretical weight: 13.73 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: Vacuolar (H+)-ATPase G subunit
Length: 118 amino acids
Theoretical weight: 13.73 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
B2GUV5 (Residues: 1-118; Coverage: 100%)
Sequence domains: Vacuolar (H+)-ATPase G subunit
V-type proton ATPase subunit H
Chain: P
Molecule details ›
Chain: P
Length: 483 amino acids
Theoretical weight: 55.94 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains:
Length: 483 amino acids
Theoretical weight: 55.94 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
A0A0G2K9J2 (Residues: 1-428; Coverage: 98%)
Sequence domains:
Type IV secretion protein Dot
Chains: Q, R, S
Molecule details ›
Chains: Q, R, S
Length: 280 amino acids
Theoretical weight: 32.15 KDa
Source organism: Legionella pneumophila
Expression system: Escherichia coli
UniProt:
Length: 280 amino acids
Theoretical weight: 32.15 KDa
Source organism: Legionella pneumophila
Expression system: Escherichia coli
UniProt:
- Canonical:
Q5ZWW6 (Residues: 1-280; Coverage: 49%)
V-type proton ATPase 116 kDa subunit a 1
Chain: a
Molecule details ›
Chain: a
Length: 838 amino acids
Theoretical weight: 96.43 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: V-type ATPase 116kDa subunit family
Length: 838 amino acids
Theoretical weight: 96.43 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
P25286 (Residues: 1-838; Coverage: 100%)
Sequence domains: V-type ATPase 116kDa subunit family
V-ATPase proteolipid subunit C-like domain-containing protein
Chain: b
Molecule details ›
Chain: b
Length: 205 amino acids
Theoretical weight: 21.62 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: ATP synthase subunit C
Length: 205 amino acids
Theoretical weight: 21.62 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
B0K022 (Residues: 1-205; Coverage: 100%)
Sequence domains: ATP synthase subunit C
V-type proton ATPase subunit S1
Chain: c
Molecule details ›
Chain: c
Length: 463 amino acids
Theoretical weight: 51.16 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains:
Length: 463 amino acids
Theoretical weight: 51.16 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
O54715 (Residues: 1-463; Coverage: 100%)
Sequence domains:
V-type proton ATPase subunit
Chain: d
Molecule details ›
Chain: d
Length: 351 amino acids
Theoretical weight: 40.34 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: ATP synthase (C/AC39) subunit
Length: 351 amino acids
Theoretical weight: 40.34 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
Q5M7T6 (Residues: 1-351; Coverage: 100%)
Sequence domains: ATP synthase (C/AC39) subunit
V-type proton ATPase subunit e 2
Chain: e
Molecule details ›
Chain: e
Length: 81 amino acids
Theoretical weight: 9.2 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: ATP synthase subunit H
Length: 81 amino acids
Theoretical weight: 9.2 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
Q5EB76 (Residues: 1-81; Coverage: 100%)
Sequence domains: ATP synthase subunit H
Similar to RIKEN cDNA 1110020A23
Chain: f
Molecule details ›
Chain: f
Length: 98 amino acids
Theoretical weight: 11 KDa
Source organism: Rattus norvegicus
UniProt:
Length: 98 amino acids
Theoretical weight: 11 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
D3ZIM6 (Residues: 1-71; Coverage: 100%)
V-type proton ATPase 16 kDa proteolipid subunit c
Chains: g, h, i, j, k, l, m, n, o
Molecule details ›
Chains: g, h, i, j, k, l, m, n, o
Length: 155 amino acids
Theoretical weight: 15.82 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: ATP synthase subunit C
Length: 155 amino acids
Theoretical weight: 15.82 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
P63081 (Residues: 1-155; Coverage: 100%)
Sequence domains: ATP synthase subunit C
Renin receptor
Chain: p
Molecule details ›
Chain: p
Length: 350 amino acids
Theoretical weight: 39.12 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains: Renin receptor-like protein
Length: 350 amino acids
Theoretical weight: 39.12 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
Q6AXS4 (Residues: 1-350; Coverage: 100%)
Sequence domains: Renin receptor-like protein