› 7v21

Electron Microscopy
3.08Å resolution

human Serine beta-lactamase-like protein LACTB truncation variant

Released:
DOI: 10.2210/pdb7v21/pdb
PDB entry 7v21 coloured by chain, front view.
PDB entry 7v21 coloured by chain, side view.
PDB entry 7v21 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB.
Zhang M, Zhang L, Guo R, Xiao C, Yin J, Zhang S, Yang M
Structure 30 685-696.e5 (2022)
PMID: 35247327
Related structures: EMD-31633

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160671 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine beta-lactamase-like protein LACTB, mitochondrial Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 421 amino acids
Theoretical weight: 47.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P83111 (Residues: 63-547; Coverage: 77%)
Gene names: LACTB, MRPL56, UNQ843/PRO1781
Sequence domains: Beta-lactamase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.08Å
Relevant EMDB volumes: EMD-31633
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Greater than the sum of parts: Mechanisms of metabolic regulation by enzyme filaments.
Hvorecny et al. (2023)
1 more