› 7v2a

Electron Microscopy
3.4Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-210335 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1208 amino acids
Theoretical weight: 133.75 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
The light chain of XG014 Fab Chains: D, F, H
Molecule details ›
Chains: D, F, H
Length: 216 amino acids
Theoretical weight: 22.63 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
The heavy chain of XG014 Chains: E, G, I
Molecule details ›
Chains: E, G, I
Length: 237 amino acids
Theoretical weight: 25.9 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
Ligand NAG 24 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-31639
Expression system: Homo sapiens

Quick links

Citations

6 review citations

Passive Immunotherapy Against SARS-CoV-2: From Plasma-Based Therapy to Single Potent Antibodies in the Race to Stay Ahead of the Variants.
Strohl et al. (2022)
5 more

4 mentions without citation

Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages.
Marcotte et al. (2024)
3 more