7v5k

Electron Microscopy
2.8Å resolution

MERS S ectodomain trimer in complex with neutralizing antibody 0722 (state 1)

Released:
Entry authors: Wang X, Zhao J, Wang Z, Zeng J, Zhang S, Wang Y
Related structures: EMD-31726

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-224846 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1189 amino acids
Theoretical weight: 130.72 KDa
Source organism: Human betacoronavirus 2c EMC/2012
Expression system: Trichoplusia ni
UniProt:
  • Canonical: K9N5Q8 (Residues: 18-1206; Coverage: 89%)
Gene names: 3, S
Sequence domains:
0722 L Chains: D, F, H
Molecule details ›
Chains: D, F, H
Length: 212 amino acids
Theoretical weight: 23.03 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
0722 H Chains: E, G, I
Molecule details ›
Chains: E, G, I
Length: 222 amino acids
Theoretical weight: 23.69 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.8Å
Relevant EMDB volumes: EMD-31726
Expression systems:
  • Trichoplusia ni
  • Homo sapiens