› 7v64

X-ray diffraction
1.56Å resolution

Crystal structure of Antibody 16A in complex with MUC1 Glycopeptide(GlycoT)

Released:
DOI: 10.2210/pdb7v64/pdb
PDB entry 7v64 coloured by chain, front view.
PDB entry 7v64 coloured by chain, side view.
PDB entry 7v64 coloured by chain, top view.
Source organisms:
Entry authors: Niu J, Xu L, Meng B, Han YB, Yang B

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-225490 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
16A fab Light chain Chain: A
Molecule details ›
Chain: A
Length: 217 amino acids
Theoretical weight: 23.54 KDa
Source organism: Mus musculus
Expression system: Trichopalpus nigribasis
16A fab Heavy chain Chain: B
Molecule details ›
Chain: B
Length: 229 amino acids
Theoretical weight: 24.75 KDa
Source organism: Mus musculus
Expression system: Trichopalpus nigribasis
Mucin-1 subunit alpha Chain: C
Molecule details ›
Chain: C
Length: 13 amino acids
Theoretical weight: 1.22 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P15941 (Residues: 925-937; Coverage: 1%)
Gene names: MUC1, PUM

Ligands and Environments

1 bound ligand:
Ligand NGA 1 x NGA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P212121
Unit cell:
a: 39.534Å b: 81.225Å c: 137.331Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.203
Expression systems:
  • Trichopalpus nigribasis
  • Not provided

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