› 7vby

Electron Microscopy
2.54Å resolution

Tom core complex with Tom20 and Tom22 subunits.

Released:
DOI: 10.2210/pdb7vby/pdb
PDB entry 7vby coloured by chain, front view.
PDB entry 7vby coloured by chain, side view.
PDB entry 7vby coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Liu DS, Sui SF
Related structures: EMD-31885

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-132112 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Mitochondrial import receptor subunit TOM20 homolog; Mitochondrial import receptor subunit TOM40 homolog Chains: B, I
Molecule details ›
Chains: B, I
Length: 828 amino acids
Theoretical weight: 90 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O96008 (Residues: 1-361; Coverage: 100%)
  • Canonical: Q15388 (Residues: 1-145; Coverage: 100%)
Gene names: C19orf1, KIAA0016, PEREC1, TOM40, TOMM20, TOMM40
Sequence domains:
Mitochondrial import receptor subunit TOM6 homolog Chains: A, F
Molecule details ›
Chains: A, F
Length: 74 amino acids
Theoretical weight: 8.01 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q96B49 (Residues: 1-74; Coverage: 100%)
Gene names: OBTP, TOM6, TOMM6
Sequence domains: Mitochondrial import receptor subunit TOM6 homolog
Mitochondrial import receptor subunit TOM5 homolog Chains: D, E
Molecule details ›
Chains: D, E
Length: 51 amino acids
Theoretical weight: 6.05 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8N4H5 (Residues: 1-51; Coverage: 100%)
Gene names: C9orf105, TOM5, TOMM5
Sequence domains: Mitochondrial import receptor subunit or translocase
Mitochondrial import receptor subunit TOM7 homolog Chains: G, J
Molecule details ›
Chains: G, J
Length: 55 amino acids
Theoretical weight: 6.26 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9P0U1 (Residues: 1-55; Coverage: 100%)
Gene names: AD-014, TOM7, TOMM07, TOMM7
Sequence domains: TOM7 family
Mitochondrial import receptor subunit TOM22 homolog Chains: C, H
Molecule details ›
Chains: C, H
Length: 142 amino acids
Theoretical weight: 15.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9NS69 (Residues: 1-142; Coverage: 100%)
Gene names: TOM22, TOMM22
Sequence domains: Mitochondrial import receptor subunit Tom22

Ligands and Environments

2 bound ligands:
Ligand PC1 11 x PC1
Ligand UND 12 x UND
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.54Å
Relevant EMDB volumes: EMD-31885
Expression system: Homo sapiens

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