EC 3.6.4.6: Vesicle-fusing ATPase
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (vesicle-fusing)
GO terms
Biochemical function:
- ubiquitin-specific protease binding
- BAT3 complex binding
- ubiquitin-modified protein reader activity
- protein-containing complex binding
- ubiquitin-like protein ligase binding
- ADP binding
- identical protein binding
- MHC class I protein binding
- K48-linked polyubiquitin modification-dependent protein binding
- deubiquitinase activator activity
- ubiquitin protein ligase binding
- polyubiquitin modification-dependent protein binding
- protein domain specific binding
- protein phosphatase binding
- ATP hydrolysis activity
- hydrolase activity
- lipid binding
- ATP binding
- protein binding
- RNA binding
- nucleotide binding
Biological process:
- positive regulation of ATP biosynthetic process
- positive regulation of ubiquitin-dependent protein catabolic process
- regulation of protein localization to chromatin
- positive regulation of oxidative phosphorylation
- cellular response to arsenite ion
- regulation of aerobic respiration
- positive regulation of Lys63-specific deubiquitinase activity
- positive regulation of protein K63-linked deubiquitination
- positive regulation of non-canonical NF-kappaB signal transduction
- cytoplasm protein quality control
- negative regulation of protein localization to chromatin
- protein-DNA covalent cross-linking repair
- autophagosome maturation
- positive regulation of canonical Wnt signaling pathway
- flavin adenine dinucleotide catabolic process
- cellular response to misfolded protein
- aggresome assembly
- endoplasmic reticulum stress-induced pre-emptive quality control
- mitotic spindle disassembly
- regulation of synapse organization
- ATP metabolic process
- negative regulation of smoothened signaling pathway
- positive regulation of protein catabolic process
- establishment of protein localization
- proteasome-mediated ubiquitin-dependent protein catabolic process
- regulation of apoptotic process
- ERAD pathway
- interstrand cross-link repair
- stress granule disassembly
- negative regulation of hippo signaling
- cellular response to heat
- cellular response to stress
- endosome to lysosome transport via multivesicular body sorting pathway
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process
- positive regulation of protein-containing complex assembly
- retrograde protein transport, ER to cytosol
- endoplasmic reticulum unfolded protein response
- translesion synthesis
- viral genome replication
- protein ubiquitination
- macroautophagy
- positive regulation of mitochondrial membrane potential
- proteasomal protein catabolic process
- DNA damage response
- autophagy
- endoplasmic reticulum to Golgi vesicle-mediated transport
- NADH metabolic process
- ubiquitin-dependent protein catabolic process
- double-strand break repair
- DNA repair
Cellular component:
- VCP-NSFL1C complex
- ATPase complex
- ficolin-1-rich granule lumen
- glutamatergic synapse
- extracellular exosome
- perinuclear region of cytoplasm
- synapse
- intracellular membrane-bounded organelle
- Derlin-1 retrotranslocation complex
- ciliary basal body
- site of double-strand break
- azurophil granule lumen
- secretory granule lumen
- VCP-NPL4-UFD1 AAA ATPase complex
- protein-containing complex
- cytoplasmic stress granule
- cytosol
- lipid droplet
- endoplasmic reticulum membrane
- endoplasmic reticulum
- cytoplasm
- nucleoplasm
- nucleus
- extracellular region
- proteasome complex
Protein families (Pfam)
InterPro annotations