Function and Biology

Cryo-EM structure of the mouse TAPL (9mer-peptide bound)

Source organism: Mus musculus
Biochemical function: ABC-type transporter activity
Biological process: transmembrane transport
Cellular component: intracellular membrane-bounded organelle

EC 7.4.2.6: ABC-type oligopeptide transporter

Reaction catalysed:
ATP + H(2)O + oligopeptide-[oligopeptide-binding protein](Side 1) = ADP + phosphate + oligopeptide(Side 2) + [oligopeptide-binding protein](Side 1)
Systematic name:
ATP phosphohydrolase (ABC-type, oligopeptide-importing)
Alternative Name(s):
  • Oligopeptide ABC transporter
  • Oligopeptide permease
  • Oligopeptide-transporting ATPase
  • OppBCDF

Sequence families

Pfam Protein families (Pfam)
PF00005
Domain description: ABC transporter
Occurring in:
  1. ABC-type oligopeptide transporter ABCB9
The deposited structure of PDB entry 7vfi contains 2 copies of Pfam domain PF00005 (ABC transporter) in ABC-type oligopeptide transporter ABCB9. Showing 1 copy in chain A.

PF00664
Domain description: ABC transporter transmembrane region
Occurring in:
  1. ABC-type oligopeptide transporter ABCB9
The deposited structure of PDB entry 7vfi contains 2 copies of Pfam domain PF00664 (ABC transporter transmembrane region) in ABC-type oligopeptide transporter ABCB9. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003439
Domain description: ABC transporter-like, ATP-binding domain
Occurring in:
  1. ABC-type oligopeptide transporter ABCB9
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. ABC-type oligopeptide transporter ABCB9
IPR011527
Domain description: ABC transporter type 1, transmembrane domain
Occurring in:
  1. ABC-type oligopeptide transporter ABCB9
IPR036640
Domain description: ABC transporter type 1, transmembrane domain superfamily
Occurring in:
  1. ABC-type oligopeptide transporter ABCB9
IPR017871
Domain description: ABC transporter-like, conserved site
Occurring in:
  1. ABC-type oligopeptide transporter ABCB9
IPR003593
Domain description: AAA+ ATPase domain
Occurring in:
  1. ABC-type oligopeptide transporter ABCB9
IPR030254
Domain description: ATP-binding cassette subfamily B member 9, six-transmembrane helical domain
Occurring in:
  1. ABC-type oligopeptide transporter ABCB9
IPR039421
Domain description: Type 1 protein exporter
Occurring in:
  1. ABC-type oligopeptide transporter ABCB9