7vnq

Electron Microscopy
2.96Å resolution

Structure of human KCNQ4-ML213 complex in nanodisc

Released:
Source organism: Homo sapiens
Related structures: EMD-32045

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-144008 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Potassium voltage-gated channel subfamily KQT member 4 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 1049 amino acids
Theoretical weight: 116.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P56696 (Residues: 2-650; Coverage: 93%)
Gene name: KCNQ4
Sequence domains:
Calmodulin-3 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 149 amino acids
Theoretical weight: 16.85 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DP25 (Residues: 1-149; Coverage: 100%)
Gene names: CALM3, CALML2, CAM3, CAMC, CAMIII
Sequence domains: EF-hand domain pair

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.96Å
Relevant EMDB volumes: EMD-32045
Expression system: Homo sapiens