› 7vsy

X-ray diffraction
2.14Å resolution

Pim1 with N82K mutation

Released:
DOI: 10.2210/pdb7vsy/pdb
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PDB entry 7vsy coloured by chain, front view.
PDB entry 7vsy coloured by chain, side view.
PDB entry 7vsy coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Hsu CY, Tzeng SR

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145753 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase pim-1 Chain: A
Molecule details ›
Chain: A
Length: 326 amino acids
Theoretical weight: 37.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P11309 (Residues: 1-313; Coverage: 100%)
Gene name: PIM1
Sequence domains: Protein kinase domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: P65
Unit cell:
a: 97.673Å b: 97.673Å c: 80.499Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.196 0.22
Expression system: Escherichia coli BL21(DE3)

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