Function and Biology Details
Reaction catalysed:
NADH + ubiquinone + 5 H(+)(Side 1) = NAD(+) + ubiquinol + 4 H(+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- NADH-quinone oxidoreductase subunit E-like
- NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding
- NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site
- Acyl carrier protein
- NADH-ubiquinone oxidoreductase, 20 Kd subunit
- 4Fe-4S ferredoxin-type, iron-sulphur binding domain
- NADH-quinone oxidoreductase, chain I
- [NiFe]-hydrogenase, large subunit
43 more domains
Structure analysis Details
Assembly composition:
hetero octadecamer (preferred)
PDBe Complex ID:
PDB-CPX-236690 (preferred)
Entry contents:
18 distinct polypeptide molecules
Macromolecules (18 distinct):
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Molecule details ›
Chain: A
Length: 431 amino acids
Theoretical weight: 47.27 KDa
Source organism: Sus scrofa
UniProt:
Sequence domains:
Length: 431 amino acids
Theoretical weight: 47.27 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A4X1SZP7 (Residues: 28-458; Coverage: 93%)
Sequence domains:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
Molecule details ›
Chain: B
Length: 176 amino acids
Theoretical weight: 20.21 KDa
Source organism: Sus scrofa
UniProt:
Sequence domains: 4Fe-4S dicluster domain
Length: 176 amino acids
Theoretical weight: 20.21 KDa
Source organism: Sus scrofa
UniProt:
- Canonical: A0A287BDC0 (Residues: 37-212; Coverage: 83%)
Sequence domains: 4Fe-4S dicluster domain
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
Acyl carrier protein
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
