EC 3.1.26.3: Ribonuclease III
Reaction catalysed:
Endonucleolytic cleavage to 5'-phosphomonoester.
Systematic name:
-
Alternative Name(s):
- RNase III
- Ribonuclease 3
GO terms
Biochemical function:
- siRNA binding
- RNA endonuclease activity, producing 5'-phosphomonoesters
- ATP hydrolysis activity
- ATP-dependent activity, acting on RNA
- ATP binding
- protein binding
- deoxyribonuclease I activity
- ribonuclease III activity
- RNA endonuclease activity
- nuclease activity
- helicase activity
- mRNA 3'-UTR binding
- RNA binding
- nucleic acid binding
Biological process:
- lncRNA catabolic process
- global gene silencing by mRNA cleavage
- cellular response to virus
- RISC complex assembly
- defense response to virus
- positive regulation of Toll signaling pathway
- positive regulation of innate immune response
- regulatory ncRNA-mediated post-transcriptional gene silencing
- heterochromatin formation
- pre-miRNA processing
- regulatory ncRNA-mediated gene silencing
- siRNA processing
- RNAi-mediated antiviral immune response
- detection of virus
- dosage compensation by hyperactivation of X chromosome
- locomotory behavior
- RNA processing
- apoptotic DNA fragmentation
- positive regulation of defense response to virus by host