Function and Biology Details
Reactions catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136770 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
E3 ubiquitin-protein ligase TRIM7
Molecule details ›
Chains: B, C, E
Length: 174 amino acids
Theoretical weight: 19.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 174 amino acids
Theoretical weight: 19.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9C029 (Residues: 338-511; Coverage: 34%)
Sequence domains:
Protein 2C
Molecule details ›
Chains: A, D, F
Length: 10 amino acids
Theoretical weight: 1.08 KDa
Source organism: Coxsackievirus
Expression system: Not provided
UniProt:
Length: 10 amino acids
Theoretical weight: 1.08 KDa
Source organism: Coxsackievirus
Expression system: Not provided
UniProt:
- Canonical: P03313 (Residues: 1420-1429; Coverage: 1%)
