› 7w7p

Electron Microscopy
3.67Å resolution

Cryo-EM structure of gMCM8/9 helicase

Released:
DOI: 10.2210/pdb7w7p/pdb
PDB entry 7w7p coloured by chain, front view.
PDB entry 7w7p coloured by chain, side view.
PDB entry 7w7p coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Structural and mechanistic insights into the MCM8/9 helicase complex.
Weng Z, Zheng J, Zhou Y, Lu Z, Wu Y, Xu D, Li H, Liang H, Liu Y
Elife 12 (2023)
PMID: 37535404
Related structures: EMD-32346

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-216220 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA helicase MCM9 Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 273 amino acids
Theoretical weight: 30.77 KDa
Source organism: Gallus gallus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: I0IUP4 (Residues: 1-273; Coverage: 23%)
Gene name: MCM9
Sequence domains: MCM OB domain
DNA helicase MCM8 Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 308 amino acids
Theoretical weight: 34.71 KDa
Source organism: Gallus gallus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: I0IUP3 (Residues: 51-358; Coverage: 37%)
Gene names: MCM8, RCJMB04_5o15
Sequence domains: MCM OB domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.67Å
Relevant EMDB volumes: EMD-32346
Expression system: Trichoplusia ni

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