› 7wc2

Electron Microscopy
3.5Å resolution

Cryo-EM structure of alphavirus, Getah virus

Released:
DOI: 10.2210/pdb7wc2/pdb
PDB entry 7wc2 coloured by chain, front view.
PDB entry 7wc2 coloured by chain, side view.
PDB entry 7wc2 coloured by chain, top view.
Source organism: Getah virus
Entry authors: Wang M, Sun ZZ, Wang JF
Related structures: EMD-32412

Function and Biology Details

Reaction catalysed: 
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 480-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178521 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike glycoprotein E1 Chains: A, D, G, J
Molecule details ›
Chains: A, D, G, J
Length: 438 amino acids
Theoretical weight: 47.62 KDa
Source organism: Getah virus
UniProt:
  • Canonical: Q5Y388 (Residues: 816-1253; Coverage: 35%)
Sequence domains: Alphavirus E1 glycoprotein
Spike glycoprotein E2 Chains: B, E, H, K
Molecule details ›
Chains: B, E, H, K
Length: 422 amino acids
Theoretical weight: 46.42 KDa
Source organism: Getah virus
UniProt:
  • Canonical: Q5Y388 (Residues: 333-754; Coverage: 34%)
Sequence domains: Alphavirus E2 glycoprotein

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-32412

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