› 7wl2

Electron Microscopy
3.25Å resolution

Mouse Pendrin in bicarbonate and iodide buffer in inward state

Released:
DOI: 10.2210/pdb7wl2/pdb
PDB entry 7wl2 coloured by chain, front view.
PDB entry 7wl2 coloured by chain, side view.
PDB entry 7wl2 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Liu Q, Zhang X, Huang H, Chen Y, Wang F, Hao A, Zhan W, Mao Q, Hu Y, Han L, Sun Y, Zhang M, Liu Z, Li GL, Zhang W, Shu Y, Sun L, Chen Z
OpenAccess logo Nat Commun 14 3012 (2023)
PMID: 37230976
Related structures: EMD-32574

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-199957 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pendrin Chains: A, B
Molecule details ›
Chains: A, B
Length: 780 amino acids
Theoretical weight: 85.77 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9R155 (Residues: 1-780; Coverage: 100%)
Gene names: Pds, Slc26a4
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.25Å
Relevant EMDB volumes: EMD-32574
Expression system: Homo sapiens

Quick links

Citations

1 review citation

SLC26 Anion Transporters.
Geertsma et al. (2024)
3 other articles