› 7wo0

Electron Microscopy
2.7Å resolution

CryoEM structure of human alpha-synuclein A53T fibril induced by calcium ions

Released:
DOI: 10.2210/pdb7wo0/pdb
PDB entry 7wo0 coloured by chain, front view.
PDB entry 7wo0 coloured by chain, side view.
PDB entry 7wo0 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wu K-P, Huang JY-C
Related structures: EMD-32637

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetradecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153505 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-synuclein Chains: A, B, C, D, E, F, G, O, P, Q, R, S, T, U
Molecule details ›
Chains: A, B, C, D, E, F, G, O, P, Q, R, S, T, U
Length: 65 amino acids
Theoretical weight: 6.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P37840 (Residues: 35-99; Coverage: 46%)
Gene names: NACP, PARK1, SNCA
Sequence domains: Synuclein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.7Å
Relevant EMDB volumes: EMD-32637
Expression system: Escherichia coli BL21(DE3)

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