7wo7

Electron Microscopy
3.8Å resolution

Locally refined region of SARS-CoV-2 Spike in complex with IgG 553-15

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-225221 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
mAb15 VH Chain: A
Molecule details ›
Chain: A
Length: 225 amino acids
Theoretical weight: 24.19 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
mAb15 VL Chain: B
Molecule details ›
Chain: B
Length: 218 amino acids
Theoretical weight: 23.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Spike protein S1 Chain: C
Molecule details ›
Chain: C
Length: 194 amino acids
Theoretical weight: 21.77 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 334-527; Coverage: 15%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-32641
Expression system: Homo sapiens