› › Structure analysis

Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK in complex with three neutralizing antibodies

Electron Microscopy
3.81Å resolution
PDB entry 7wp6 coloured by chain, front view.
PDB entry 7wp6 coloured by chain, side view.
PDB entry 7wp6 coloured by chain, top view.
Source organisms:
Assembly composition:
hetero heptamer (preferred)
Entry contents: 7 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Spike protein S2' and IG-heavy chain and IG-light kappa chain and IG-heavy chain and IG-heavy chain and IG-light kappa chain and IG-light kappa chain
hide full assembly name
Multimeric state: hetero heptamer
Accessible surface area: 37783.3 Å2
Buried surface area: 10488.21 Å2
Dissociation area: 650.62 Å2
Dissociation energy (ΔGdiss): -3.84 kcal/mol
Dissociation entropy (TΔSdiss): 13.31 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-225224

Macromolecules

36H6 heavy chain
Chain: B
Length: 119 amino acids
Theoretical weight: 13.13 KDa
Source organism: Mus musculus
InterPro:
36H6 heavy chain in PDB entry 7wp6, assembly 1, front view.
36H6 heavy chain in PDB entry 7wp6, assembly 1, side view.
36H6 heavy chain in PDB entry 7wp6, assembly 1, top view.
Molecule details ›

Search similar proteins

83H7 light chain
Chain: C
Length: 104 amino acids
Theoretical weight: 11.43 KDa
Source organism: Mus musculus
InterPro:
83H7 light chain in PDB entry 7wp6, assembly 1, front view.
83H7 light chain in PDB entry 7wp6, assembly 1, side view.
83H7 light chain in PDB entry 7wp6, assembly 1, top view.
Molecule details ›

Search similar proteins

83H7 heavy chain
Chain: D
Length: 118 amino acids
Theoretical weight: 13.03 KDa
Source organism: Mus musculus
InterPro:
83H7 heavy chain in PDB entry 7wp6, assembly 1, front view.
83H7 heavy chain in PDB entry 7wp6, assembly 1, side view.
83H7 heavy chain in PDB entry 7wp6, assembly 1, top view.
Molecule details ›

Search similar proteins

Spike protein S1
Chain: F
Length: 189 amino acids
Theoretical weight: 21.34 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P0DTC2 (Residues: 333-521; Coverage: 15%)
Gene names: 2, S
Pfam: Betacoronavirus spike glycoprotein S1, receptor binding
InterPro:
Spike protein S1 in PDB entry 7wp6, assembly 1, front view.
Spike protein S1 in PDB entry 7wp6, assembly 1, side view.
Spike protein S1 in PDB entry 7wp6, assembly 1, top view.
Molecule details ›

Search similar proteins

85F7 heavy chain
Chain: H
Length: 118 amino acids
Theoretical weight: 13.16 KDa
Source organism: Mus musculus
InterPro:
85F7 heavy chain in PDB entry 7wp6, assembly 1, front view.
85F7 heavy chain in PDB entry 7wp6, assembly 1, side view.
85F7 heavy chain in PDB entry 7wp6, assembly 1, top view.
Molecule details ›

Search similar proteins

36H6 light chain
Chain: I
Length: 113 amino acids
Theoretical weight: 12.44 KDa
Source organism: Mus musculus
InterPro:
36H6 light chain in PDB entry 7wp6, assembly 1, front view.
36H6 light chain in PDB entry 7wp6, assembly 1, side view.
36H6 light chain in PDB entry 7wp6, assembly 1, top view.
Molecule details ›

Search similar proteins

85F7 light chain
Chain: L
Length: 106 amino acids
Theoretical weight: 11.28 KDa
Source organism: Mus musculus
InterPro:
85F7 light chain in PDB entry 7wp6, assembly 1, front view.
85F7 light chain in PDB entry 7wp6, assembly 1, side view.
85F7 light chain in PDB entry 7wp6, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links