Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105869 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Angiotensin-converting enzyme
Molecule details ›
Chain: A
Length: 692 amino acids
Theoretical weight: 80.78 KDa
Source organism: Pipistrellus pipistrellus
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 692 amino acids
Theoretical weight: 80.78 KDa
Source organism: Pipistrellus pipistrellus
Expression system: Homo sapiens
UniProt:
- Canonical:
A0A7J7V5I6 (Residues: 21-712; Coverage: 88%)
Sequence domains:
Spike glycoprotein
Molecule details ›
Chain: B
Length: 194 amino acids
Theoretical weight: 21.84 KDa
Source organism: Coronavirus Neoromicia/PML-PHE1/RSA/2011
Expression system: Homo sapiens
UniProt:
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Length: 194 amino acids
Theoretical weight: 21.84 KDa
Source organism: Coronavirus Neoromicia/PML-PHE1/RSA/2011
Expression system: Homo sapiens
UniProt:
- Canonical: U5NJG5 (Residues: 380-573; Coverage: 14%)
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Ligands and Environments
1 bound ligand:
No modified residues
