7wpq

Electron Microscopy
3.27Å resolution

Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 3.27 angstron resolution (2 units)

Released:
Source organism: Homo sapiens
Related structures: EMD-32688

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137578 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
von Willebrand antigen 2 Chains: A, B, E, G
Molecule details ›
Chains: A, B, E, G
Length: 741 amino acids
Theoretical weight: 81.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P04275 (Residues: 23-763; Coverage: 27%)
Gene names: F8VWF, VWF
Sequence domains:
von Willebrand factor Chains: C, D, F, H
Molecule details ›
Chains: C, D, F, H
Length: 490 amino acids
Theoretical weight: 54.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P04275 (Residues: 764-1241; Coverage: 17%)
Gene names: F8VWF, VWF
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.267Å
Relevant EMDB volumes: EMD-32688
Expression system: Homo sapiens