7wqt

Electron Microscopy
4.3Å resolution

Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (VWF tube)

Released:
Source organism: Homo sapiens
Related structures: EMD-32713

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 32-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137573 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
von Willebrand antigen 2 Chains: A, B, E, F, G, H, I, J, K, L, M, N, O, P, Q, R
Molecule details ›
Chains: A, B, E, F, G, H, I, J, K, L, M, N, O, P, Q, R
Length: 741 amino acids
Theoretical weight: 81.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P04275 (Residues: 23-763; Coverage: 27%)
Gene names: F8VWF, VWF
Sequence domains:
von Willebrand factor Chains: C, D, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f
Molecule details ›
Chains: C, D, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f
Length: 490 amino acids
Theoretical weight: 54.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P04275 (Residues: 764-1241; Coverage: 17%)
Gene names: F8VWF, VWF
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 4.3Å
Relevant EMDB volumes: EMD-32713
Expression system: Homo sapiens