7ws1

Electron Microscopy
3.4Å resolution

Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero undecamer (preferred)
PDBe Complex ID:
PDB-CPX-210375 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1288 amino acids
Theoretical weight: 142.32 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:
510A5 light chain Chains: D, F, H, J
Molecule details ›
Chains: D, F, H, J
Length: 108 amino acids
Theoretical weight: 11.68 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
510A5 heavy chain Chains: E, G, I, K
Molecule details ›
Chains: E, G, I, K
Length: 125 amino acids
Theoretical weight: 13.74 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-32740
Expression system: Homo sapiens