Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105048 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Angiotensin-converting enzyme
Molecule details ›
Chain: A
Length: 739 amino acids
Theoretical weight: 85.79 KDa
Source organism: Mammalia
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 739 amino acids
Theoretical weight: 85.79 KDa
Source organism: Mammalia
Expression system: Escherichia coli
UniProt:
- Canonical:
A0A452CBT6 (Residues: 1-739; Coverage: 92%)
Sequence domains:
Spike protein S1
Molecule details ›
Chain: B
Length: 190 amino acids
Theoretical weight: 21.62 KDa
Source organism: Severe acute respiratory syndrome coronavirus
Expression system: Homo sapiens
UniProt:
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Length: 190 amino acids
Theoretical weight: 21.62 KDa
Source organism: Severe acute respiratory syndrome coronavirus
Expression system: Homo sapiens
UniProt:
- Canonical: P59594 (Residues: 321-502; Coverage: 15%)
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
