7wt7

Electron Microscopy
3.4Å resolution

SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 1)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-225390 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (5 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1270 amino acids
Theoretical weight: 141.28 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-210, 211-211, 215-1273; Coverage: 99%)
Gene names: 2, S
Sequence domains:
Heavy chain of Fab 9A8 Chain: H
Molecule details ›
Chain: H
Length: 122 amino acids
Theoretical weight: 13 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Light chain of Fab 9A8 Chain: D
Molecule details ›
Chain: D
Length: 107 amino acids
Theoretical weight: 11.82 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-32770
Expression system: Homo sapiens