7wtx

Electron Microscopy
3.1Å resolution

Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B1

Released:
Source organism: Homo sapiens
Related structures: EMD-32804

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 34-mer (preferred)
PDBe Complex ID:
PDB-CPX-140345 (preferred)
Entry contents:
33 distinct polypeptide molecules
1 distinct RNA molecule
Macromolecules (34 distinct):
Small ribosomal subunit protein uS7 Chain: F
Molecule details ›
Chain: F
Length: 204 amino acids
Theoretical weight: 22.91 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46782 (Residues: 1-204; Coverage: 100%)
Gene name: RPS5
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein eS12 Chain: M
Molecule details ›
Chain: M
Length: 132 amino acids
Theoretical weight: 14.54 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P25398 (Residues: 1-132; Coverage: 100%)
Gene name: RPS12
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Small ribosomal subunit protein uS19 Chain: P
Small ribosomal subunit protein uS9 Chain: Q
Small ribosomal subunit protein eS17 Chain: R
Small ribosomal subunit protein uS13 Chain: S
Small ribosomal subunit protein eS19 Chain: T
Small ribosomal subunit protein eS25 Chain: Z
Small ribosomal subunit protein eS28 Chain: c
Ubiquitin-ribosomal protein eS31 fusion protein Chain: f
Small ribosomal subunit protein uS2 Chain: A
Small ribosomal subunit protein eS1 Chain: B
Small ribosomal subunit protein uS5 Chain: C
Small ribosomal subunit protein eS4, X isoform Chain: E
Small ribosomal subunit protein eS6 Chain: G
Small ribosomal subunit protein eS7 Chain: H
Small ribosomal subunit protein eS8 Chain: I
Small ribosomal subunit protein uS4 Chain: J
Small ribosomal subunit protein uS17 Chain: L
Small ribosomal subunit protein uS15 Chain: N
Small ribosomal subunit protein uS11 Chain: O
Small ribosomal subunit protein eS21 Chain: V
Small ribosomal subunit protein uS8 Chain: W
Small ribosomal subunit protein uS12 Chain: X
Small ribosomal subunit protein eS24 Chain: Y
Small ribosomal subunit protein eS27 Chain: b
Small ribosomal subunit protein eS30 Chain: e
RNA-binding protein PNO1 Chain: x
RNA-binding protein NOB1 Chain: y
Pre-rRNA-processing protein TSR1 homolog Chain: u
Bystin Chain: w
Protein LTV1 homolog Chain: t
RRP12-like protein Chain: K
18S Ribosomal RNA Chain: 2

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-32804