7wve

Electron Microscopy
3.11Å resolution

CT-mut (D523K,D524K,E527K) TLR3-poly(I:C) complex

Released:
Related structures: EMD-32851

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-127478 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct RNA molecules
Macromolecules (3 distinct):
Toll-like receptor 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 680 amino acids
Theoretical weight: 77.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: O15455 (Residues: 27-697; Coverage: 76%)
Gene name: TLR3
Sequence domains:
RNA (46-MER) Chain: E
Molecule details ›
Chain: E
Length: 46 nucleotides
Theoretical weight: 13.99 KDa
Source organism: synthetic construct
Expression system: Not provided
RNA (46-MER) Chain: F
Molecule details ›
Chain: F
Length: 46 nucleotides
Theoretical weight: 15.14 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.11Å
Relevant EMDB volumes: EMD-32851
Expression systems:
  • Trichoplusia ni
  • Not provided