› 7x39

X-ray diffraction
2.85Å resolution

Structure of CIZ1 bound ERH

Released:
DOI: 10.2210/pdb7x39/pdb
PDB entry 7x39 coloured by chain, front view.
PDB entry 7x39 coloured by chain, side view.
PDB entry 7x39 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Molecular basis for the recognition of CIZ1 by ERH.
Wang X, Xie H, Zhu Z, Zhang J, Xu C
FEBS J 290 712-723 (2023)
PMID: 36047590

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160811 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cip1-interacting zinc finger protein; Enhancer of rudimentary homolog Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 158 amino acids
Theoretical weight: 17.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P84090 (Residues: 1-104; Coverage: 100%)
  • Canonical: Q9ULV3 (Residues: 539-569; Coverage: 4%)
Gene names: CIZ1, ERH, LSFR1, NP94, ZNF356
Sequence domains: Enhancer of rudimentary

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17B1
Spacegroup: P1
Unit cell:
a: 44.451Å b: 48.668Å c: 73.879Å
α: 85.83° β: 75.08° γ: 63.31°
R-values:
R R work R free
0.221 0.218 0.267
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Thirty Years with ERH: An mRNA Splicing and Mitosis Factor Only or Rather a Novel Genome Integrity Protector?
Kozlowski P. (2023)
1 other article