› 7x6s

Electron Microscopy
3.4Å resolution

lymphocytic choriomeningitis virus RNA-dependent RNA polymerase (LCMV-L protein)

Released:
DOI: 10.2210/pdb7x6s/pdb
PDB entry 7x6s coloured by chain, front view.
PDB entry 7x6s coloured by chain, side view.
PDB entry 7x6s coloured by chain, top view.
Source organism: Lymphocytic choriomeningitis virus (strain Armstrong)
Primary publication:
Structure basis for allosteric regulation of lymphocytic choriomeningitis virus polymerase function by Z matrix protein.
Liu L, Wang P, Liu A, Zhang L, Yan L, Guo Y, Xiao G, Rao Z, Lou Z
OpenAccess logo Protein Cell (2023)
PMID: 37038286
Related structures: EMD-33026

Function and Biology Details

Reaction catalysed: 
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-240237 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-directed RNA polymerase L Chain: A
Molecule details ›
Chain: A
Length: 2210 amino acids
Theoretical weight: 254.89 KDa
Source organism: Lymphocytic choriomeningitis virus (strain Armstrong)
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P14240 (Residues: 1-2210; Coverage: 100%)
Gene names: L, Segment L
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand MN 1 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-33026
Expression system: unidentified baculovirus

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