7xav

Electron Microscopy
2.87Å resolution

Structure of somatostatin receptor 2 bound with lanreotide.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-225586 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Somatostatin receptor type 2 Chain: A
Molecule details ›
Chain: A
Length: 563 amino acids
Theoretical weight: 63.27 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P30874 (Residues: 1-361; Coverage: 98%)
Gene name: SSTR2
Sequence domains: 7 transmembrane receptor (rhodopsin family)
Guanine nucleotide-binding protein G(i) subunit alpha-1 Chain: B
Molecule details ›
Chain: B
Length: 354 amino acids
Theoretical weight: 40.47 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P63096 (Residues: 1-354; Coverage: 100%)
Gene name: GNAI1
Sequence domains: G-protein alpha subunit
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: C
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: D
ScFv16 Chain: E
Lanreotide Chain: F

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Resolution: 2.87Å
Relevant EMDB volumes: EMD-33100
Expression systems:
  • Spodoptera frugiperda
  • Not provided