PDB 7xk3 structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

NADH + ubiquinone + n Na(+)(Side 1) = NAD(+) + ubiquinol + n Na(+)(Side 2)

Biochemical function:

oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

Biological process:

sodium ion transport

Cellular component:

membrane

Sequence domains:

10 more domains

Structure analysis Details

Assembly composition:

hetero hexamer (preferred)

Assembly name:

Na(+)-translocating NADH-quinone reductase (preferred)

PDBe Complex ID:

PDB-CPX-107567 (preferred)

Entry contents:

6 distinct polypeptide molecules

Macromolecules (6 distinct):

Na(+)-translocating NADH-quinone reductase subunit A Chain: A

Molecule details ›

Chain: A
Length: 446 amino acids
Theoretical weight: 48.68 KDa
Source organism: Vibrio cholerae O395
Expression system: Vibrio cholerae
UniProt:

Canonical: A5F5X1 (Residues: 1-446; Coverage: 100%)

Gene names: VC0395_A1884, VC395_2411, nqrA
Sequence domains:

Na(+)-translocating NADH-quinone reductase subunit B Chain: B

Molecule details ›

Chain: B
Length: 415 amino acids
Theoretical weight: 45.39 KDa
Source organism: Vibrio cholerae O395
Expression system: Vibrio cholerae
UniProt:

Canonical: A5F5X0 (Residues: 1-415; Coverage: 100%)

Gene names: VC0395_A1883, VC395_2410, nqrB
Sequence domains: NQR2, RnfD, RnfE family

Na(+)-translocating NADH-quinone reductase subunit C Chain: C

Molecule details ›

Chain: C
Length: 257 amino acids
Theoretical weight: 27.65 KDa
Source organism: Vibrio cholerae O395
Expression system: Vibrio cholerae
UniProt:

Canonical: A5F5Y7 (Residues: 1-257; Coverage: 100%)

Gene names: VC0395_A1882, VC395_2409, nqrC
Sequence domains: FMN-binding domain

Na(+)-translocating NADH-quinone reductase subunit D Chain: D

Molecule details ›

Chain: D
Length: 210 amino acids
Theoretical weight: 22.85 KDa
Source organism: Vibrio cholerae O395
Expression system: Vibrio cholerae
UniProt:

Canonical: A5F5Y6 (Residues: 1-210; Coverage: 100%)

Gene names: VC0395_A1881, VC395_2408, nqrD
Sequence domains: Rnf-Nqr subunit, membrane protein

Na(+)-translocating NADH-quinone reductase subunit E Chain: E

Molecule details ›

Chain: E
Length: 198 amino acids
Theoretical weight: 21.48 KDa
Source organism: Vibrio cholerae O395
Expression system: Vibrio cholerae
UniProt:

Canonical: A5F5Y5 (Residues: 1-198; Coverage: 100%)

Gene names: VC0395_A1880, VC395_2407, nqrE
Sequence domains: Rnf-Nqr subunit, membrane protein

Na(+)-translocating NADH-quinone reductase subunit F Chain: F

Molecule details ›

Chain: F
Length: 414 amino acids
Theoretical weight: 45.94 KDa
Source organism: Vibrio cholerae O395
Expression system: Vibrio cholerae
UniProt: