› 7xlb

Electron Microscopy
3.44Å resolution

Cryo-EM structure of human pannexin 2

Released:
DOI: 10.2210/pdb7xlb/pdb
PDB entry 7xlb coloured by chain, front view.
PDB entry 7xlb coloured by chain, side view.
PDB entry 7xlb coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Cryo-EM structure of human heptameric pannexin 2 channel
Zhang H, Wang S, Zhang Z, Hou M, Du C, Zhao Z, Vogel H, Li Z, Yan K, Zhang X, Lu J, Liang Y, Yuan S, Wang D, Zhang H
Nat Commun 14 1118- (2023)
Related structures: EMD-33276

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188714 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pannexin-2 Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 410 amino acids
Theoretical weight: 46.3 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q96RD6 (Residues: 1-410; Coverage: 61%)
Gene name: PANX2
Sequence domains: Innexin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.44Å
Relevant EMDB volumes: EMD-33276
Expression system: Homo sapiens

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