› 7xwu

X-ray diffraction
2Å resolution

Ketoreductase CpKR mutant - M1

Released:
DOI: 10.2210/pdb7xwu/pdb
PDB entry 7xwu coloured by chain, front view.
PDB entry 7xwu coloured by chain, side view.
PDB entry 7xwu coloured by chain, top view.
Source organism: Candida parapsilosis
Entry authors: Chen C, Zheng YC, Pan J, Xu JH

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-216642 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NAD-dependent epimerase/dehydratase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 377 amino acids
Theoretical weight: 41.52 KDa
Source organism: Candida parapsilosis
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: G8B6C8 (Residues: 1-341; Coverage: 100%)
Gene name: CPAR2_100480
Sequence domains: NAD dependent epimerase/dehydratase family

Ligands and Environments

2 bound ligands:
Ligand NDP 2 x NDP
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P1
Unit cell:
a: 41.271Å b: 53.562Å c: 79.565Å
α: 78.75° β: 81.65° γ: 78.15°
R-values:
R R work R free
0.204 0.202 0.238
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

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