7y0v

X-ray diffraction
2.48Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-210028 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
5549-Fab Chain: H
Molecule details ›
Chain: H
Length: 233 amino acids
Theoretical weight: 24.74 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
5549-Fab Chain: L
Molecule details ›
Chain: L
Length: 213 amino acids
Theoretical weight: 22.6 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Spike protein S1 Chain: R
Molecule details ›
Chain: R
Length: 225 amino acids
Theoretical weight: 25.81 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P0DTC2 (Residues: 325-541; Coverage: 17%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL10U2
Spacegroup: C2221
Unit cell:
a: 64.77Å b: 138.91Å c: 178.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.211 0.268
Expression systems:
  • Homo sapiens
  • Trichoplusia ni