Function and Biology

Ni-Carbonic Anhydrase II complexed with 3NPA after UV at 180 K

Source organism: Homo sapiens
Biochemical function: metal ion binding
Biological process: regulation of chloride transport
Cellular component: extracellular exosome

EC 4.2.1.69: Cyanamide hydratase

Reaction catalysed:
Urea = cyanamide + H(2)O
Systematic name:
Urea hydro-lyase (cyanamide-forming)
Alternative Name(s):
  • Urea hydro-lyase

EC 4.2.1.1: Carbonic anhydrase

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O
Systematic name:
Carbonic acid hydro-lyase (carbon-dioxide-forming)
Alternative Name(s):
  • Anhydrase
  • Carbonate anhydrase
  • Carbonate dehydratase
  • Carbonate hydro-lyase
  • Carbonic acid anhydrase
  • Carbonic anhydrase A
  • Carbonic dehydratase
  • Carboxyanhydrase

Sequence family

Pfam Protein family (Pfam)
PF00194
Domain description: Eukaryotic-type carbonic anhydrase
Occurring in:
  1. Carbonic anhydrase 2
The deposited structure of PDB entry 7y2w contains 1 copy of Pfam domain PF00194 (Eukaryotic-type carbonic anhydrase) in Carbonic anhydrase 2. Showing 1 copy in chain A.