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Cryo-EM structure of the monomeric human CAF1LC-H3-H4 complex

Source organism: Homo sapiens
Biochemical function: protein binding
Biological process: nucleosome assembly
Cellular component: protein-containing complex

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. Chromatin assembly factor 1 subunit B
  2. Histone-binding protein RBBP4
The deposited structure of PDB entry 7y5u contains 5 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Histone-binding protein RBBP4. Showing 5 copies in chain D [auth C].
The deposited structure of PDB entry 7y5u contains 3 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Chromatin assembly factor 1 subunit B. Showing 3 copies in chain E [auth B].

PF15511
Domain description: Centromere kinetochore component CENP-T histone fold
Occurring in:
  1. Histone H4
The deposited structure of PDB entry 7y5u contains 1 copy of Pfam domain PF15511 (Centromere kinetochore component CENP-T histone fold) in Histone H4. Showing 1 copy in chain C [auth E].

PF00125
Domain description: Core histone H2A/H2B/H3/H4
Occurring in:
  1. Histone H3.1
The deposited structure of PDB entry 7y5u contains 1 copy of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H3.1. Showing 1 copy in chain B [auth D].

PF12265
Domain description: Histone-binding protein RBBP4 or subunit C of CAF1 complex
Occurring in:
  1. Histone-binding protein RBBP4
The deposited structure of PDB entry 7y5u contains 1 copy of Pfam domain PF12265 (Histone-binding protein RBBP4 or subunit C of CAF1 complex) in Histone-binding protein RBBP4. Showing 1 copy in chain D [auth C].

PF15539
Domain description: CAF1 complex subunit p150, region binding to CAF1-p60 at C-term
Occurring in:
  1. Chromatin assembly factor 1 subunit A

PF12253
Domain description: Chromatin assembly factor 1 subunit A
Occurring in:
  1. Chromatin assembly factor 1 subunit A
The deposited structure of PDB entry 7y5u contains 1 copy of Pfam domain PF12253 (Chromatin assembly factor 1 subunit A) in Chromatin assembly factor 1 subunit A. Showing 1 copy in chain A.

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