7ydp

Electron Microscopy
3.1Å resolution

Cryo-EM structure of CD97/miniGs complex

Released:
Source organisms:
Primary publication:
Structural basis of CD97 activation and G-protein coupling.
Cell Chem Biol (2023)
PMID: 37673067
Related structures: EMD-33755

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-235832 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Adhesion G protein-coupled receptor E5 subunit beta Chain: R
Molecule details ›
Chain: R
Length: 307 amino acids
Theoretical weight: 34.55 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: C
Molecule details ›
Chain: C
Length: 71 amino acids
Theoretical weight: 7.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Chain: A
Nb35 Chain: D
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: B

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-33755
Expression systems:
  • Spodoptera frugiperda
  • Escherichia coli