7yg4

Electron Microscopy
3.1Å resolution

Structure of WTAP-VIRMA in the m6A writer complex

Released:
Source organism: Homo sapiens
Related structures: EMD-33807

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-172155 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein virilizer homolog Chain: A
Molecule details ›
Chain: A
Length: 1107 amino acids
Theoretical weight: 123.72 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q69YN4 (Residues: 381-1486; Coverage: 61%)
Gene names: KIAA1429, MSTP054, VIRMA
Pre-mRNA-splicing regulator WTAP Chains: B, E
Molecule details ›
Chains: B, E
Length: 295 amino acids
Theoretical weight: 34.11 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q15007 (Residues: 1-273; Coverage: 69%)
Gene names: KIAA0105, WTAP
Sequence domains: WTAP/Mum2p family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-33807
Expression system: Spodoptera frugiperda