› 7yim

Electron Microscopy
2.6Å resolution

Cryo-EM structure of human Alpha-fetoprotein

Released:
DOI: 10.2210/pdb7yim/pdb
PDB entry 7yim coloured by chain, front view.
PDB entry 7yim coloured by chain, side view.
PDB entry 7yim coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Uniform thin ice on ultraflat graphene for high-resolution cryo-EM.
Zheng L, Liu N, Gao X, Zhu W, Liu K, Wu C, Yan R, Zhang J, Gao X, Yao Y, Deng B, Xu J, Lu Y, Liu Z, Li M, Wei X, Wang HW, Peng H
OpenAccess logo Nat Methods (2022)
PMID: 36522503
Related structures: EMD-33861

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136193 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-fetoprotein Chain: A
Molecule details ›
Chain: A
Length: 609 amino acids
Theoretical weight: 68.76 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P02771 (Residues: 1-609; Coverage: 100%)
Gene names: AFP, HPAFP
Sequence domains: Serum albumin family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.6Å
Relevant EMDB volumes: EMD-33861
Expression system: Homo sapiens

Quick links

Citations

1 review citation

Ultrafast micro/nano-manufacturing of metastable materials for energy.
Cui et al. (2024)
17 other articles

3 mentions without citation

Analysis of aptamer-target binding and molecular mechanisms by thermofluorimetric analysis and molecular dynamics simulation.
Zhang et al. (2023)
2 more