› 7yld

X-ray diffraction
2.8Å resolution

Two monobodies recognizing the conserved epitopes of SARS-CoV-2 N antigen applicable to the broad COVID-19 diagnosis

Released:
DOI: 10.2210/pdb7yld/pdb
PDB entry 7yld coloured by chain, front view.
PDB entry 7yld coloured by chain, side view.
PDB entry 7yld coloured by chain, top view.
Source organisms:
Entry authors: Hu M, Du Y, Sun R, Hao Q

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-243435 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nucleoprotein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 132 amino acids
Theoretical weight: 14.4 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DTC9 (Residues: 47-174; Coverage: 31%)
Gene name: N
Sequence domains: Coronavirus nucleocapsid
NN2 Chains: E, F, G, I
Molecule details ›
Chains: E, F, G, I
Length: 94 amino acids
Theoretical weight: 10.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P1
Unit cell:
a: 52.551Å b: 74.303Å c: 87.451Å
α: 108.51° β: 104.22° γ: 96.67°
R-values:
R R work R free
0.288 0.286 0.343
Expression system: Escherichia coli

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