7ymz

Electron Microscopy
4.39Å resolution

Cryo-EM structure of MERS-CoV spike protein, intermediate conformation

Released:
Entry authors: Hsu STD, Chang NE, Weng ZW, Yang TJ, Draczkowski P
Related structures: EMD-33948

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
PDBe Complex ID:
PDB-CPX-125457 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1369 amino acids
Theoretical weight: 150.65 KDa
Source organism: Human betacoronavirus 2c EMC/2012
Expression system: Homo sapiens
UniProt:
  • Canonical: K0BRG7 (Residues: 17-1291; Coverage: 94%)
Gene name: S
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, FUC
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.39Å
Relevant EMDB volumes: EMD-33948
Expression system: Homo sapiens