7yo5

Electron Microscopy
3.9Å resolution

Cryo-EM structure of RCK1 mutated human Slo1 apo

Released:
Source organism: Homo sapiens
Entry authors: Yamanouchi D, Nureki O
Related structures: EMD-33982

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-171393 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-activated potassium channel subunit alpha-1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 1060 amino acids
Theoretical weight: 119.37 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q12791 (Residues: 66-643, 644-1179; Coverage: 85%)
  • Best match: Q12791-6 (Residues: 66-126)
Gene names: KCNMA, KCNMA1, SLO
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-33982
Expression system: Homo sapiens