› 7yrj

X-ray diffraction
2.35Å resolution

S-adenosylmethionine sensor upstream of mTORC1

Released:
DOI: 10.2210/pdb7yrj/pdb
PDB entry 7yrj coloured by chain, front view.
PDB entry 7yrj coloured by chain, side view.
PDB entry 7yrj coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zhang H, Li XZ, Wen YN

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194331 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
S-adenosylmethionine sensor upstream of mTORC1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 236 amino acids
Theoretical weight: 27.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9W138 (Residues: 67-302; Coverage: 78%)
Gene names: CG3570, Samtor
Sequence domains: 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2

Ligands and Environments

1 bound ligand:
Ligand SFG 4 x SFG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P21
Unit cell:
a: 64.333Å b: 78.896Å c: 100.096Å
α: 90° β: 96.4° γ: 90°
R-values:
R R work R free
0.242 0.24 0.291
Expression system: Escherichia coli

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